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Nimesh D. Desai, MD, PhD

Cardiac Surgery
headshot of Nimesh D. Desai, MD, PhD
4.9 with 650 ratings

Sees patients age 18 and up

Nimesh D. Desai, MD, PhD

Cardiac Surgery
4.9 with 650 ratings

Sees patients age 18 and up

  • Director, Thoracic Aortic Surgery Research Program
  • Director, Penn Aorta Center
  • Associate Professor of Surgery at the Hospital of the University of Pennsylvania
  • Dr. Desai is a Penn Medicine physician.
Call 215-615-4949 Request Appointment

Meet Dr. Desai

I direct the Penn Aorta Center, where we provide comprehensive care in a new way. Rather than just manage the challenge in front of us, we deliver a lifetime of support.

In my practice, I specialize in aortic valve procedures, including transcatheter and minimally invasive replacements and complex surgical repairs. I also perform valve-sparing aortic root replacements, aortic aneurysm repairs, and the Ross procedure. I’ve completed more than 4,000 heart procedures — 2,500 of them involving heart valves.

My research focuses on improving procedures for the aorta and aortic valve. I run clinical trials testing new therapies and technologies aimed at making treatment more effective and easier to undergo. And I lead aortic groups for the Society of Thoracic Surgeons overseeing data collection and monitoring surgical risk.

I became interested in heart surgery as a child. Years later, I completed a fellowship at Penn in aortic and endovascular surgery. It’s always satisfying to come up with a solution that restores quality of life when someone arrives with a complex challenge. For that to happen, I listen to each person’s needs and wishes and work with our team to find the best recommendation.

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